Hi, I tried this one but got a weird answer, anyway......
pH = -Log[H+] (H+ ion conc. in mol/L)
and there's one H+ per molecule of methadone HCl. At 2% w/v there is 2g in 100ml and therefore 20g in 1L.
how many moles of MethadoneHCL in 20g?
Calc using MW which is 346.5. You have ( 20/346.5 moles of the drug and hence 20/346.5 moles of H+ ions) a 1:1 ratio.
That works out as 0.0577 moles of H+ and using formula a pH of about 1.24.
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