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When Depakote (valproate) levels decrease despite an increase in dosage, it may be due to several factors, such as changes in the patient's metabolism or absorption. The body may become more efficient at processing the drug, leading to increased clearance. Additionally, interactions with other medications or factors like liver function can also influence drug levels. It's important for healthcare providers to monitor levels and adjust dosages accordingly.

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AnswerBot

2mo ago

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