1987
No, methotrexate is a form of chemotherapy and an immunosuppressant. It is used to treat autoimmune disease and some forms of cancer.
Methotrexate is usually yellow.
No, methotrexate does not contain anticholinergics. Methotrexate is an antimetabolite medication primarily used to treat certain cancers and autoimmune diseases, while anticholinergics are a class of drugs that block the action of the neurotransmitter acetylcholine. These two types of medications have different mechanisms of action and are used for different therapeutic purposes.
Methotrexate uses insulin needles.
Yes, methotrexate is gluten free.
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Methotrexate was developed in the 1940s by Dr. Sidney Farber, an American physician and pathologist. He initially used it as a treatment for leukemia in children. Farber's work laid the foundation for the drug's use in cancer treatment and later for autoimmune diseases. Methotrexate is now widely used in various medical applications, including oncology and rheumatology.
No. Methotrexate is not a controlled medication.
Yes, headaches are a common side effect of methotrexate.
caution Due to aspirin's effect on platelet aggregation and GI mucosa, aspirin should be used cautiously in patients with thrombocytopenia following treatment with antineoplastic agents due to an increased risk of bleeding.[5717] In general, because certain antineoplastic agents can cause clinically significant thrombocytopenia, they may increase the risk of aspirin-associated bleeding (i.e. GI bleeding, inhibited platelet aggregation, and prolonged bleeding time). Also, aspirin may mask signs of infection such as fever and pain in patients following treatment with antineoplastic agents or immunosuppressives.[6859] Aspirin, ASA should be used with caution in patients receiving immunosuppressive therapy. Although usually seen with large salicylate doses, aspirin may displace mercaptopurine, 6-MP from secondary binding sites, resulting in bone marrow toxicities and blood dyscrasias.[5232] Special consideration should be given to myelosuppressed patients prior to receiving aspirin. Due to the thrombocytopenic effects of methotrexate,[5067] when used as an antineoplastic agent, an additive risk of bleeding may be seen in patients receiving concomitant anticoagulants, platelet inhibitors (also see salicylates), strontium-89 chloride, or thrombolytic agents. Caution should be exercised when salicylates are given in combination with methotrexate. Since both are weak acids, salicylates can impair the renal secretion of methotrexate and increase the risk of methotrexate toxicity. Salicylates can also displace methotrexate from protein-binding sites.[5067] Although the risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any of these drugs be used cautiously with methotrexate even when methotrexate is used in low doses for the treatment of rheumatoid arthritis. A significantly higher incidence of leukopenia has been reported in patients taking aspirin during methotrexate therapy. Bismuth subsalicylate may have similar effects. In addition, large doses of salicylates (>= 3-4 g/day) can cause hypoprothrombinemia,[5170] an additional risk factor for bleeding. Caution should be exercised when aspirin is given in combination with methotrexate. Concomitant administration of salicylates with high-dose methotrexate therapy has been reported to elevate and prolong serum concentrations of methotrexate resulting in deaths from severe hematologic and gastrointestinal toxicity. Although the risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any salicylate be used cautiously with methotrexate even when lower doses of methotrexate are given for the treatment of rheumatoid arthritis or psoriasis. Elderly patients and patients with renal impairment may be at particular risk. As both methotrexate and salicylates are weak acids, aspirin can impair the renal secretion of methotrexate and increase the risk of methotrexate toxicity. Salicylates can also displace methotrexate from protein-binding sites.[5067] [5232]
Methotrexate is used for the treatment of head and neck cancers. It is a mild immunosuppressant.
It's important to consult a healthcare professional before combining hydroxycut and methotrexate. Hydroxycut is a weight loss supplement that may contain various stimulants, which could potentially interact with methotrexate, a medication used for autoimmune diseases and cancer. Such interactions could affect the effectiveness of methotrexate or increase the risk of side effects. Always seek personalized medical advice to ensure safety and efficacy.