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It depends on your opiate tolerance level, but for first time users you should start feeling it around 3-6 hours after application.

A number of factors affect the dosage rate as well - adhesion to the skin, body temperature (which regulates the dose), and again, your tolerance level. Doctors typically prescribe the lowest dose first, and it's important to know that the dosage equivalence table (Fentanyl-Morphine) used to determine the initial dose is purposely skewed to the lower end for safety reasons. As such, its not uncommon for first time users to not get the desired effect on the first patch dose, and it's something you need to tell your doctor about.

Keep a record on how well (or not) it's affecting you so that you can show your doctor you need to increase if you need to.

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15y ago

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