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Discovery of penicillin was one of the most dramatic events in the history of Pharmacology. Sir Alexander Flaming was working in his laboratory in 1928. A stale piece of bread was there in his lab. He observed that there were colonies of bacteria on the same. He observed that around the colonies of some fungi, there was the clear zones. He concluded that the fungi are producing some substance, which is inhibiting the growth of the bacteria.

There were lot of casualties during the second world war. There was desperate need to find the drug to treat the infected wounds. Dr. Florry and Chain decided to treat a critical patient with penicillin. They did not know the dose. A round figure was selected. 5000 I U. Now you know that this is very less dose. Thanks God for it worked! The patient stared to recover. But died, when the stock of penicillin was exhausted. The young doctor used to go to hospital, in London, on his bicycle to bring the urine of the patient to recollect the penicillin. I have been wondering from last four decades about how he collected penicillin from the urine! The ultimate result was invention of the ultimate antibiotic, penicillin.

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10y ago

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