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Louis Pasteur, a french doctor, was the first to explain the principles of vacccination.

His first human vaccination was on a child against rabies in 1885.

But a century before, Peter Plett, a German teacher and Edward Jenner, a English doctor practised the first vaccination separetly at the same time.

They inoculated the vaccine (the cow version of variola) to people who will be acknowledeged as immuned against variola.

Some historians also say that inoculation of variola had already been made in ancient China.

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