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Beta-blockers are contraindicated in vasospastic angina because they can exacerbate vasospasm by blocking beta-2 adrenergic receptors, which normally mediate vasodilation. In patients with vasospastic angina, the primary issue is inappropriate vasoconstriction, and using beta-blockers may worsen this condition by limiting the body's ability to dilate blood vessels during episodes of angina. Instead, calcium channel blockers or nitrates are preferred as they promote vasodilation and help alleviate symptoms.

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2mo ago

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Why beta blockers are contraindicated in vasospastic angina?

Beta blockers are contraindicated in vasospastic angina because they can potentially exacerbate vasospasm. These medications decrease heart rate and contractility, which can lead to unopposed alpha-adrenergic receptor stimulation in the coronary arteries, causing them to constrict further. This can worsen ischemia and provoke anginal episodes. Instead, calcium channel blockers or long-acting nitrates are typically preferred to help relieve vascular tension and prevent spasms.


Is there a cure for vasospastic angina?

There is no definitive cure for vasospastic angina, but it can be effectively managed with lifestyle changes and medications. Calcium channel blockers and nitrates are commonly prescribed to help alleviate symptoms and prevent episodes. Patients are also advised to avoid triggers such as stress, smoking, and extreme temperatures. Regular follow-ups with a healthcare provider are essential for effective management.


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