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Amlodipine can interact with digoxin primarily due to its effects on the body's metabolism and cardiovascular system. Amlodipine may increase the plasma concentration of digoxin by affecting renal clearance and altering hemodynamics, potentially leading to digoxin toxicity. Additionally, both medications impact heart rate and contractility, which can compound their effects and increase the risk of adverse reactions. Therefore, careful monitoring is essential when these drugs are used together.

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5mo ago

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What are the main drug interactions of amlodipine?

Amlodipine can interact with several medications, primarily affecting blood pressure and heart function. Notable interactions include strong CYP3A4 inhibitors like ketoconazole and ritonavir, which can increase amlodipine levels and enhance its effects, potentially leading to hypotension. Conversely, drugs like rifampin can reduce amlodipine's effectiveness by increasing its metabolism. Additionally, combining amlodipine with other antihypertensives may lead to additive effects, requiring careful monitoring of blood pressure.


How do lamotrigine and amlodipine interact?

Lamotrigine and amlodipine do not have significant interactions that are commonly noted. Lamotrigine is primarily an anticonvulsant and mood stabilizer, while amlodipine is a calcium channel blocker used to treat hypertension. However, it's always advisable for patients to consult with their healthcare provider before starting new medications, as individual responses can vary. Monitoring for side effects is important when taking multiple medications.


Is it safe to take digoxin and ibuprofen?

Aspirin, an NSAID, is contraindicated in the use with Digoxin due to the fact that it increases Digoxin levels in th blood and could lead to Digoxin Toxicity.


What functional groups are present in Amlodipine?

Amlodipine contains an amino group (-NH2), a dihydropyridine ring, and a methyl ester group.


What is the effect of amlodipine to your unborn baby?

i had a high blood pressure my OB recomend me to take amlodipine. what is the effect amlodipine to my unborn baby?


Is it safe to take Claritin, Motrin, and Ativan with St. John wort?

574 medications are known to interact with st. john's wort. Includes amlodipine, gabapentin, atorvastatin.


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Aspirin, tramadol, and digoxin may interact with each other, but the clinical significance of these interactions can vary. Aspirin can increase the risk of gastrointestinal bleeding when used with tramadol, while tramadol may also enhance the effects of digoxin, potentially leading to increased toxicity. It's essential to consult a healthcare professional for personalized advice and monitoring when using these medications together.


Can you take Benadryl and digoxin together?

Can you take Benadryl if you are taking Digoxin


Can allopurinol be taken with amlodipine besylate 5mg?

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If this question is referring to Digoxin, then the antidote is Digoxin Imunefab.


Can you eat grapefruit when taking amlodopine?

Yes, you can generally eat grapefruit while taking amlodipine; however, it's important to do so in moderation. Grapefruit itself does not significantly interact with amlodipine like it does with some other medications. Nevertheless, it's always best to consult your healthcare provider for personalized advice regarding your diet and medications.


How many milliliter of digoxin do you give if a doctor's order states give digoxin 0.3 mg IM and you have digoxin 500mcg to 2ml?

It's 1.2 mL.