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Because, when paired together, promethazine is an opiate potenciater. many people get sleepy taking promethazine by itself.... When they're mixed, it makes the opiate if choice even stronger; hence the reason it is matched with codeine in "lean," or "drank."

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13y ago

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Not at all. Promethazine is helpful in reducing nausea. Hydrocodone is a narcotic pain medication found in Vicodin and a few other pills (Lortab and Norco are the only ones I can think of off the top of my head). Simply put -- Hydrocodone will work best for you if you are suffering from either post-op pain or moderate-to-severe pain. It has a history of abuse and has a moderate risk of addiction. Promethazine mainly helps with the nausea that can occur during post-op. It doesnt make you feel euphoric like Vicodin will, it's not a narcotic, so the chances of you becoming addicted to THIS medication is slim to none.


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