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The pacemaker, primarily located in the sinoatrial (SA) node of the heart, fires spontaneously and rhythmically due to its unique properties of automaticity. It possesses specialized pacemaker cells that have unstable resting membrane potentials, allowing them to reach the threshold for action potentials without external stimuli. This intrinsic ability is facilitated by the influx of sodium and calcium ions, which leads to depolarization. As a result, the SA node generates regular electrical impulses that initiate each heartbeat, maintaining the heart's rhythm.

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2w ago

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