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The local tenderness and sometimes redness, swelling, and hardness in the area where a flu vaccine has been given is the most common side effect of the injection. It is the local muscle tissue noticing and reacting to the "foreign invaders" in the vaccine (the virus particles in the vaccine). Although the invaders can't make you sick, they trick your body into thinking they can, so your body goes to work trying to increase circulation to the area and sending the immune system cells that fight viruses to the area. That response can make your arm sore. It can last for 2 to 3 days, and sometimes it is even worse the second day. Don't try to avoid moving the arm, using it will help it get better faster, so work through the discomfort and use it normally as much as you can. You may find it helps to put a moist warm compress (washcloth or something similar) on the area that hurts for 20 minutes and see if it makes it feel better.

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15y ago

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