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The warning is primarily for caregivers rather than the patient, as exposure to Fentanyl, even in small amounts, can make people who aren't opiate tolerant pretty sick. About a 1/4" of the patch edge is strictly adhesive; the rest is an adhesive membrane that allows the drug to pass through to the skin, and from there to the bloodstream.

Many seriously ill or terminal cancer patients require several 100mcg patches and they can't apply them alone, so the person applying them is at risk of accidental exposure.

Of course for the patient who uses them regularly, the only thing you need to worry about is getting skin oil / dirt on the adhesive edges.

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15y ago

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