Why would a cortisone shot not work?

Answer 1

A cortisone shot may not work for several reasons, including incorrect diagnosis, where the source of pain is not related to inflammation that cortisone targets. Additionally, individual variations in response to corticosteroids can affect effectiveness, and underlying conditions such as joint damage or structural issues may limit the shot's impact. Other factors, such as timing of the injection, dosage, or technique used, can also contribute to the lack of relief.