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I have been looking into this. It doesn't seem anyone feels there are health risks. I can tell you this: Wellbutrin does not get along with any other drug. It seems like anything that disrupts the workings of Wellbutrin is spoiled by it. It is a very jealous drug, and that's why it helps with nicotine addiction. I have always been very adventerous with substances. I have not found anything that agrees with Wellbutrin. You will be hard pressed to devise a combo I haven't already attempted. Again, I can't speak medically on this, but your enjoyment will be affected. As for actual pain relief, it helps. I broke my ankle and was on Norcos for months. But, you will deal with the conflicts I speak of. Basically, Wellbutrin will amplify the negative aspects of any chemical experience. With Hydrocodone, this means increased irritability, depression, etc. That is my observation, after 11 years on/off with Wellbutrin - added to a very stubborn taste for altered states.

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16y ago

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