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Yes, in fact marijuana does interact with other drugs such as Vicodin (brand name). Often drugs use the same enzymes, if your body is busy breaking down one drug, the other is more active. There are more than 500 different drugs (offered with over 3000 different brand names) that interact, several quite strongly. Side effects can include severe dizziness, confusion, shallow breathing respiratory distress, and in severe instances coma or death. Its like alcohol..some things are fine..some things cause annoying side effects (like antibiotics and the pill..your no longer on the pill its negated while on certain antibiotics) but sometimes mixing one drug with another causes severe interactions. A match does nothing to water, little to pure oxygen, but put a match to the wrong chemical and you have an explosive reaction- same with marijuana and specific drugs (I have a PhD in neuroscience). check drugs . com also see cannabis interactions on Webmd and mayoclinic

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