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The belief in Manifest Destiny, the idea that the United States was destined to expand across North America, had profound and often devastating effects on Native American tribes. It justified the forced removal of Native peoples from their ancestral lands, leading to widespread displacement, violence, and the erosion of their cultures. Policies like the Indian Removal Act of 1830 resulted in tragic events such as the Trail of Tears, where thousands of Native Americans were forcibly relocated, suffering immense hardship and loss. Overall, Manifest Destiny contributed to the systematic marginalization and devastation of Native American communities.

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