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European colonization had a profound impact on Native Americans, leading to significant population decline due to diseases like smallpox, against which they had no immunity. Colonization also resulted in the loss of land and resources, as settlers encroached on indigenous territories, disrupting traditional lifestyles and economies. Additionally, many Native American cultures faced assimilation pressures and violence, leading to the erosion of languages, traditions, and social structures. Overall, the consequences of European colonization were devastating, reshaping the demographic and cultural landscape of the Americas.

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