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By 1550, Spain had solidified its control over vast territories in the Americas through a combination of military conquests, strategic alliances, and the establishment of colonial administrations. Key events included the conquests of the Aztec and Inca Empires, led by figures like Hernán Cortés and Francisco Pizarro, which allowed Spain to access immense wealth and resources. Additionally, the Spanish Crown implemented systems such as encomiendas to regulate labor and extract tribute from Indigenous populations, further entrenching their dominance in the region. These factors collectively enabled Spain to maintain and expand its influence during the mid-16th century.

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