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In 1665, the Great Plague of London occurred, resulting in the deaths of an estimated 100,000 people, about a quarter of the city's population at the time. The outbreak led to widespread fear and social disruption, prompting many to flee the city. Additionally, the year marked the publication of Isaac newton's groundbreaking work in mathematics and physics, particularly in calculus and the laws of motion, which would later influence the Scientific Revolution.

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1w ago

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