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Can't say this is all of them, but here's some:

1. Few if any civilized facilities:

-- paved roads

-- easy access to manufactured goods

-- access to repair for broken items

-- access to professional medical services

2. Unfamiliar territory (this has several implications):

-- sometimes no European folk had been through the territory yet, so no maps or experienced guides

-- didn't know what yearly weather patterns were like to know how bad the winter might be or how much or reliable the precipitation would be for farming

-- didn't know the quality of the soil for agriculture

-- didn't know which native plants were edible or useful for other purposes

3. Sometimes hostile natives

4. Sometimes hostile neighbors:

-- earlier prospectors/trappers didn't always appreciate settlers horning in on the land

-- some con men and robbers preyed on isolated settlers

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15y ago

What else can I help you with?