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A bulge loop is a structural feature found in RNA molecules, characterized by a loop that contains one or more unpaired nucleotides, or a bulge, which protrudes from the double-stranded regions. This configuration allows for flexibility and can play a crucial role in RNA folding, stability, and function. Bulge loops can influence the binding of proteins and other molecules, thereby affecting the RNA's biological activity. They are important in various processes, including gene regulation and the formation of ribozymes.

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