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Cleopatra successfully fought for power aganist his brother Ptolemy XIII and her sister Arsinoe IV. She also tried, but failed, to overcome the power of Rome and the civil wars between the Romans.

Julius Caesar reached Egypt in pursuit of his enemy Pompey. Ptolemy had Pompey killed and his head offered to Caesar. Horrified, Caesar allied with Cleopatra, who became his lover, and supported her in a civil war against her Ptolemy and Arsinoe. Caesar won. Ptolemy was killed in battle and Arsinoe was taken to Rome as a prisoner. She was then exiled to a sanctuary of Artemis in Turkey. Caesar won the war for Cleopatra.

After Caesar's death, Mac Antony took charge of the Roman territories in the Eastern Mediterranean. Cleopatra became his lover. She got Mac Antony to kill Arsinoe. Marc Antony partitioned the eastern Mediterranean giving partS of it to Cleopatra, the three sons she had with him and the son she had had with Caesar. However, Octavian (later called Augustus) declared war on Cleopatra as an excuse to fight Mac Antony to gain sole power in Rome. Octavian defeated them in a naval battle and landed in Egypt. He overcome their forces and Marc Antony and Cleopatra committed suicide.

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