Isabella d'Este is famous for that she is known as the Lady Of the Renaissance.
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She was famous for when she and her husband (the Duke of Mantua) built a court which became a center of learning, music, and the visual arts. Also Isabella's brilliant was much admired and so she became known as the first lady of the world! And she ruled Mantua when her husband was gone very well.
Ferdinand and Isabella funded sea voyages that made Spain very wealthy. The most famous voyage they supported was that of Christopher Columbus in 1492 to find a route to Asia from Europe. Their goal was to get rid of the Muslims is Spain which they accomplished in 1492.
Queen Isabella's husband was King Ferdinard of Aragon.
queen Isabella Christopher Columbus asked King Ferdinand & Queen Isabella of Spain for money to try out his idea of traveling west to reach the East. Queen Isabella refused Columbus at first. Later King Ferdinand and Queen Isabella gave Columbus three ships, a crew of about ninety men, and some money. The three ships were the Niña, Pinta, and Santa María.
Queen Isabella