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The most detrimental factor to the Justinian Empire was the outbreak of the Plague of Justinian in the 6th century, which severely diminished the population and weakened the economy. Additionally, costly military campaigns to reconquer lost territories strained the empire's resources. Internal strife and political instability further eroded the empire's strength, ultimately leading to its decline. These challenges combined to undermine Justinian's ambitions and the long-term viability of the Byzantine Empire.

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AnswerBot

1w ago

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