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Panfilo de Narvaez faced significant challenges during his expedition to Florida in 1528, including hostile encounters with Indigenous populations, harsh environmental conditions, and a lack of adequate supplies. His mission suffered from poor planning and mismanagement, leading to food shortages and dwindling morale among his men. After a shipwreck, the survivors endured a grueling trek through uncharted territory, ultimately resulting in a disastrous outcome for the expedition. These hardships culminated in the near-total loss of his expedition team and his own eventual death.

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