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The two most common were malaria (that was transferred by mosquitoes) and scurvy (that sailors contracted from low vitamin C levels)

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Deseases in the 1500s?

Some prominent diseases in the 1500s were Malaria, Tuberculosis, (Known as Consumption) Smallpox, Parroticitis, Gangrene, Yellow Fever, and many others, though most diseases were simply diagnosed as Consumption. Scurvy was also common among sailors. Malaria was quite possibly the most deadly disease of the 1500s and 1600s. It was transferred by Mosquito bite, and was very common in tropical areas. The cure was quanine, but was largely unavailable due to it's exclusive growth in South America. Tuberculosis, or Consumption, was one of the most common diseases in the 16th and 17th centuries, though this is primarily attributed to the fact that nearly all diseases were labelled "consumption," because of the limited medical knowledge of the time.