Queen Isabella and King Ferdinand
Spain
Yes!
Never, they were conqured By Portuguese in the early 1500s.
In the early 1500s, Spain was ruled by King Ferdinand II of Aragon and Queen Isabella I of Castile, who were married in 1469 and united their kingdoms. Their reign is noted for the completion of the Reconquista in 1492 and the sponsorship of Christopher Columbus’s voyages to the New World. After Isabella's death in 1504, Ferdinand continued to rule until his own death in 1516, during which time their grandson, Charles I, began to rise in prominence.
the empire was conquered by the moroccans in the late 1500s.
Spain.
Spain
Spain was the country that controlled the seas by the late 1500s, thanks to its powerful navy and extensive overseas territories. This dominance was largely due to the success of Spanish explorers and conquests in the Americas, which brought significant wealth and resources back to Spain.
Hippocrates, a physician born in ancient Greece was the first to describe manifestations of the disease and relate them to the time of year and area where the patients lived when contracting the disease. However, the discovery of the protozoal cause of malaria wasn't discovered until 1889 by Alphonse Laveran.
Spain
The Anglo-Spanish War of the 1500s was a result of King Phillip the Second's suppression of the growth to the Protestant religion in Catholic Spain. It was caused by England's Act of Supremacy, which threatened the power of the Pope.
France!
Spain
SPAIN conquered most of Central America in the 1500s.
Akbar.
haenery
in the late 1500s