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Spanish conquistadors were able to control and defeat powerful Native American empires primarily due to their advanced military technology, including firearms, steel weapons, and cavalry, which gave them a significant advantage in battle. Additionally, they exploited existing rivalries among indigenous groups, forming alliances with some tribes against others. The spread of diseases brought by Europeans, such as smallpox, decimated native populations, further weakening their ability to resist conquest. Finally, the conquistadors' determination and strategic leadership played crucial roles in their successes.

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