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No, duloxetine is not a monoamine oxidase inhibitor (MAOI). It is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI), which works by increasing the levels of serotonin and norepinephrine in the brain. MAOIs, on the other hand, inhibit the monoamine oxidase enzyme, which breaks down neurotransmitters. Therefore, duloxetine and MAOIs have different mechanisms of action and therapeutic uses.

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