Taxol, or paclitaxel, is a chemotherapy drug that stabilizes microtubules and inhibits cell division in eukaryotic cells, particularly cancer cells. Bacterial cells, however, lack microtubules and the cytoskeletal structures that Taxol targets, rendering the drug ineffective against them. Additionally, bacterial cell division relies on different mechanisms, such as binary fission, which are unaffected by Taxol's action on eukaryotic microtubules. As a result, Taxol does not have any significant impact on bacterial growth or division.
Taxol is usually a drug which is prescribed for the illness cancer. This is commonly used to treat 3 types of cancer these types include breast, ovarian and non small cell lung cancer.
Taxol was first discovered in Taxus brevifolia Nutt in 1971.
Confirerophyta is the phylum where taxol was originally found.
Taxol was first discovered in Taxus brevifolia Nutt in 1971.
Because Taxol can induce the assembly of tubulin into microtubules and stabalizes them to the extent that mitosis of cancer cells is disrupted.
'The Himalayan yew (Taxus wallachiana)', a chemical compound called 'taxol', is extracted from the bark, needles and twigs. The drug is now the biggest selling anti-cancer drug in the world. It is found on the hills of Himachal Pradesh and Arunachal Pradesh
Taxol is derived from the bark of the Pacific yew tree, scientifically known as Taxus brevifolia. In the plant, taxol functions as a defense mechanism against herbivores and pathogens by stabilizing the microtubules, thereby inhibiting cell division. This property is what makes taxol valuable in medicine, especially for its use in cancer treatment.
Taxol is a chemical substance derived from a yew tree of the pacific coast.
The chemotherapy drug Taxol, or paclitaxel, was originally derived from the bark of the Pacific yew tree (Taxus brevifolia). Discovered in the 1960s, it was found to have significant anti-cancer properties, particularly effective against ovarian and breast cancers. The extraction process from the yew tree was initially complex and unsustainable, leading to the development of semi-synthetic methods for production.
Taxol binds to ß-tubulin to promote microtubule assembly and it stabilises the microtubules and messes up the equilibrium between tubulin and microtubule. A cell with stable microtubules proceeds to programmed cell death without dividing. Nathalie Narraidoo University of Nottingham
There are several functional groups in Taxol, including ester, benzene ring, hydroxyl, and amide groups.