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Electrical switching centers, called 'synapses' are found throughout the nervous systems of humans, other vertebrates, and insects. Muscles, glands, and nerve fibers called 'neurons' are stimulated or inhibited by the constant firing of signals across these synapses. Stimulating signals are usually carried by a chemical called 'acetylcholine' (a-see-till-ko-leen). Stimulating signals are discontinued by a specific type of cholinesterase enzyme, acetylcholinesterase, which breaks down the acetylcholine. These important chemical reactions are usually going on all the time at a very fast rate, with acetylcholine causing stimulation and acetylcholinesterase ending the signal. If cholinesterase-affecting insecticides are present in the synapses, however, this situation is thrown out of balance. The presence of cholinesterase inhibiting chemicals prevents the breakdown of acetylcholine. Acetylcholine can then build up, causing a "jam" in the nervous system. Thus, when a person receives to great an exposure to cholinesterase inhibiting compounds, the body is unable to break down the acetylcholine
What else can I help you with?
What has the author Patsy R Fowler written?
Patsy R. Fowler has written: 'Problems in aerial application' -- subject(s): Cholinesterase-inhibiting insecticides, Organophosphorus compounds
Is cholinesterase inhibitor a neurohormone?
No, cholinesterase inhibitors are not neurohormones. They are a class of medications that inhibit the enzyme cholinesterase, which breaks down the neurotransmitter acetylcholine in the synaptic cleft. By preventing the breakdown of acetylcholine, these inhibitors enhance cholinergic transmission, typically used in the treatment of conditions like Alzheimer's disease. Neurohormones, on the other hand, are hormones produced by neurosecretory cells that act on distant targets in the body.
What has the author Linda L Carlock written?
Linda L. Carlock has written: 'Blood and brain cholinesterase inhibition and associated behaviors from exposure to phosphorodithioate organophosphorus pesticides' -- subject(s): Effect of pesticides on, Organophosphorus compounds, Pesticides and wildlife, Toxicology, Northern bobwhite, Cholinesterase-inhibiting insecticides, Birds, Phosphorus
What interactions do cholinesterase inhibitors have?
Some cholinesterase inhibitors should be used with caution in persons with asthma or lung disease, as cholinesterase inhibitors may interact with theophylline, a drug commonly used to treat both conditions.
What is the purpose of cholinesterase inhibitors?
Cholinesterase inhibitors are drugs that block the activity of an enzyme in the brain called cholinesterase. Cholinesterase breaks apart the neurotransmitter acetylcholine, which is vital for the transmission of nerve impulses.
The enzyme cholinesterase causes acetylcholine to what?
Decompose
What is the antidote for Neuromuscular blocker toxicity?
cholinesterase inhibitor
What is an anticholinesterase?
An anticholinesterase is an agent which inhibits the activity of cholinesterase.
Can cholinesterase inhibitors help chronic fatigue syndrome or fibromyalgia?
From what I've read in an article in the Developing Healthy Habits newsletter, inhibiting cholinesterase will increase your symptoms, because cholinesterase is what makes your muscles flexible. Fruits and vegetables in the nightshade family contain Solanine, which is a powerful cholinesterase inhibitor, which will interfere with muscle movement. Nightshades include tomatoes, potatoes, eggplant, blueberries, peppers and tobacco products.
What do actylcholine and cholinesterase do?
Acetylcholine is a neurotransmitter responsible for transmitting signals in the nervous system. Cholinesterase is an enzyme that breaks down acetylcholine into choline and acetate, terminating the neurotransmitter's signal transmission.
Are xanthines cholinesterase inhibitors?
No, xanthines are not cholinesterase inhibitors. Xanthines are a group of compounds that include caffeine and theophylline, which act primarily as adenosine receptor antagonists. Cholinesterase inhibitors, on the other hand, are a different class of drugs used to increase the levels of acetylcholine in the brain for the treatment of conditions like Alzheimer's disease.
What is a commonly used cholinesterase inhibitor that is used therapeutically?
atropine
