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When the mosquito drinks blood, she injects an anticoagulant to keep the blood from clotting. The anticoagulant, like all foreign proteins, activates the immune system. This causes a local allergic reaction around the bite.

Only female mosquitoes drink the blood of humans and other animals to develop her eggs properly before they are laid. Male mosquitoes feed on fruits and plant juices.

The answer is, since these bites can bring malaria and other diseases, we have evolved to react to the bite by itching.
It has something to do with the Enzymes in the Mosquito's salivary glands which are secreted from the Proboscis ( What punctures the skin) of the Mosquito which is deposited under the skin after they puncture it, this then causes an irritation which results in the itching sensation.

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10y ago

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