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Calcium has at least 2 rules in the body. One is to stregnthen bones so that old people do not get curved backs (osteoporosis, bones with holes). When they are old. A more important rule of Calcium is to increae or decrease the transmission of a nerve impulse. Ca 2 + has a 2 plus charge. When a nerve inpulse arrives ina neuron (nerve cell), it had a negative charge. The nerve impulse is inside the nerve cell membrane. Ca 2 + will be outside the nerve cell membrane. Calcium of + charge will be attracted to the - charge of the nerve impulse. So Ca 2+ will cross the cell membrane into the nerve cell. The basic result is that a + charge crosses into the membrane towards a - charge. The Calcium 2 + is attracted to the nerve impulse made of electorn, a negative charge. A third neuron acting on the 1 st neuron can increase or decrease the transmission of the neurotransmitter from the 1st neuron. To inhibit the neuron transmission, a third neuroin acting on the first will cause GABA to close membrane pores. This will allow less Ca2+ to enter the membrane from outside the 1st cell, thus reducing the amount of neurotransmitter passed to the 2nd (object) cell. Thsi action of reducing the amount of nerotransmitter passed to the object cell (#2) is called presynaptic inhibition. A third cell can cause pre-synaptic facilitation, an increase of neurotransmitter passed from cell 1 to cell the object cell (#2) by opening the pores through which the Ca 2+ can pass accross the cell membrane in cell 1. There is an increae of nerotransmitter pessed to the object cell. Simply put withoput Ca2+ our nerves would not work, and our bones would become like noodles.

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