Blood contains high levels of citrate. Calcium gluconate helps counteract or buffer the effect of the citrate which can include chelating, inability to coagulant or clot which can cause hypocalcemia, and citrate toxicity due to the lover's slow processing of citrate.
Donated blood is stored in a blood bag containing anticoagulant. Mostly, citrate is used as anticoagulant. Without that being mixed with donated blood, the blood will clot by itself within minutes and will be of no further use for transfusing in to a patient who needs blood. So adding citrate is a must. Now, the citrate binds with the calcium in the blood and thus depletes the concentration of free calcium in blood. So the recipient may suffer from complications resulting from low level of free calcium in blood. One or two bag is no problem, but if three or more bags of blood is given to a person in a row within a day, then body can not cope up with the rate of decline of free calcium. Therefore, extra calcium is to be given for that purpose. Any calcium salt would serve the purpose, but calcium gluconate has some additional advantages in this regard.
A blood donor is a person who donates blood for use in transfusion.
A blood donor is a person who donates blood for use in transfusion.
to keep the blood from coagulating
Citrate in blood binds to calcium ions, forming complexes that are not available for biological functions. This decreases the amount of free calcium in the blood, leading to hypocalcemia. Additionally, citrate can chelate calcium in the blood, further reducing the level of ionized calcium available for use in blood clotting and nerve function.
One example of how to use transfusion in a sentence is: Transfusions are used to replace lost components of the blood.
Oh yes, blood transfusion is done with real blood, although there have been experiments with artificial blood, and sometimes blood plasma is used rather than whole blood, when there is a problem in getting the right blood type.
If a transfusion is given to a patient from a person with a different blood type, the immune system will attack those blood cells. This can cause a severe reaction in the patient, including shock to the immune system or death.
Someone with type B blood can receive type O blood during a transfusion.
Dr. George Crile reported on the use of direct blood transfusions between humans in 1903. This marked a significant advancement in the field of blood transfusion and laid the foundation for modern blood transfusion practices.
Use of blood components is a more efficient way to use the blood supply, because blood that has been processed (fractionated) into components can be used to treat more than one person.
Blood Transfusion or use of Synthetic Haemoglobin is the only treatment. It si to temporaily stabilize the patient so that other treatments work. Use of Synthetic Haemoglobin has a longer life than blood transfusion. There is a chance that the transfused blood may be destroyed by patient's immune system.