How did barry marshall test his hypothesis?

Answer 1

Barry Marshall tested his hypothesis that Helicobacter pylori bacteria caused peptic ulcers by self-experimentation. In 1984, he ingested a culture of the bacteria to demonstrate its effects, which resulted in him developing gastritis and ulcer-like symptoms. This bold approach provided evidence supporting his theory and helped shift the medical understanding of ulcer causes from stress and diet to bacterial infection. His work ultimately led to effective treatments for peptic ulcers.