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The structure of certain materials, such as crystals or biological cells, can limit size due to constraints like lattice spacing or membrane integrity. In crystals, the regular arrangement of atoms restricts growth beyond a specific size, while in cells, the semi-permeable membrane can only support efficient nutrient exchange and waste removal within a limited volume. Additionally, structural integrity may be compromised if size exceeds certain thresholds, leading to mechanical failure. Thus, these inherent structural characteristics impose natural limits on size.

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