Goserelin is an GnRH receptor agonist and bings stronger than GnRH. Due to the constant activation of the GnRH receptor (Goserelin binds really strong; Superagonist) the cell internalizes the receptor -> Downregulation.
GnRH stands for Gonadotropin-Releasing Hormone. It is a hormone produced in the hypothalamus that stimulates the release of other hormones involved in reproduction, such as LH and FSH.
No, GnRH or gonadotropin releasing hormone is not a steroid, but rather a peptide (type of protein) hormone.
GnRH, short for gonadotropin-releasing hormone, is released by the part of the brain known as the hypothalamus. At the beginning of the menstual cycle, the hypothalamus releases GnRH. The GnRH then stimulates a different part of the brain, the pituitary gland, to produce two hormones, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Seems like it could be referring to up/down regulation of the receptors in your brain that give you effects from drugs. Downregulation is a way for your brain to adjust/protect itself. also.. I'm da ish trick what what
hypothalamic hormone
FSH and LH
GnRH
GnRH (gonadotropin-releasing hormone) is secreted and produced by a specific group of neurons located in the hypothalamus of the brain. These neurons release GnRH in a pulsatile manner, regulating the production and release of hormones involved in the control of the reproductive system.
it hasn't been tried yet... or so im told
The answer is Anterior Pituitary
what i learned in class was that GnRH was produced by the Hypothalamus gland, and it stimulated the release of FSH and LH in the Anterior lobe of the pituitary gland.
Steroid abuse can cause downregulation of the Androgen Receptor, therefore reducing the effects of testosterone and other androgens in vivo.