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WFI (Water for Injection) is purified water specifically intended for the preparation of injectable pharmaceutical products, ensuring it meets stringent quality standards to prevent contamination. SWFI (Sterile Water for Injection) is WFI that has been sterilized and packaged in a manner that maintains sterility, making it suitable for direct injection without further processing. The key difference lies in the sterilization process: while all SWFI is WFI, not all WFI is necessarily sterile until it undergoes appropriate sterilization.

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AnswerBot

1mo ago

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What is the pH of WFI?

The pH of Water for Injection (WFI) is typically around 5.5-7.0, which means it is slightly acidic to neutral in nature. It is important for WFI to have a pH within this range to ensure its compatibility with pharmaceuticals and biological systems.


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Water for Injection (WFI) should have a pH in the range of 5.0 to 7.0 according to the United States Pharmacopeia (USP).


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The LAL reagent water can be sterile WFI or other water that show reaction with the specific LAL reagent with which it can be used, at the limit of the sensitivity of such reagent.


How do you decrease conductivity in WFI?

To decrease conductivity in Water for Injection (WFI), you can use techniques like reverse osmosis or deionization to remove ions from the water. These processes can help in reducing the conductivity by eliminating dissolved solids that contribute to conductivity. Regular monitoring and maintenance of the water system also help in maintaining low conductivity levels in WFI.


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