Yes! The adjective "supersubtle" was coined circa 1590-1600 CE.
Some spices have a subtle aroma. The wink she gave was no subtle clue.
The prefix "co-" could be used with the act.
The prefix for "cavated" could be "de-" as in "decavated."
You could add the prefix af- to it to make the word affluent.
The prefix "inter-" could be used with "cept" to form the word "intercept."
The opposite of subtle could be obvious. Depending on the context, it could also be overt, harsh, forthright, or coarse.
Some spices have a subtle aroma. The wink she gave was no subtle clue.
The prefix "co-" could be used with the act.
The prefix for "cavated" could be "de-" as in "decavated."
You could add the prefix af- to it to make the word affluent.
"Possibility" doesn't have a prefix. You could add the prefix im- to it to make the word impossibility.
The prefix "inter-" could be used with "cept" to form the word "intercept."
"Cost" doesn't have a prefix. You could add the prefix ac- to it to make the word "accost."
Renumber is a prefix numbered is a suffix
One possible prefix for "rewrite" could be "re-".
A possible prefix for "climbe" could be "dis-" as in "disclimbe."
"Patients" doesn't have a prefix. You could add the prefix in- to it to get the word inpatients.