What does ique puedo hacer mean in English?

Answer 1

Y que puedo hacer - And what can I do

Depending on the vocal inflection and/or context, it could be an idiom meaning "What do you want me do do about it?"

However that saying is generally "Y Yo que puedo hacer?"

Answer 2

"Ique puedo hacer" does not have a clear translation in English as "ique" does not appear to be a recognized word. It could be a typo or mispronunciation. If you can provide more context, we may be able to give a more accurate translation.