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It's not really a "prefix" so much as a word. It could be an indication that the compound word has to do with flies (the insect), as in "flypaper". It could also have to do with something else called a "fly", such as "flyspace" in the theatre (it's the area over the stage where the "flies" ... objects that are "flown", or hoisted on ropes or chains ... hang).

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11y ago

What else can I help you with?