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The form 'my wife and me' is the objective form, the object of a verb or a preposition.

examples:

The agent advised my wife and me to make the trip in April. (direct object of the verb; advised us)

The agent recommended the best trip for my wife and me. (object of the preposition; for us)

The form 'my wife and I' is the subjectiveform, the subject of a sentence or clause.

Example:

My wife and I enjoyed the trip. (subject of the sentence; we enjoyed)

Their guests, my wife and I included, receive first class treatment. (subject of the clause; we were included)

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11y ago

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