anti
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Yes, "anti" is the root word in "antigen." "Anti" means against, and an antigen is a molecule that triggers the immune system's response.
The root in the word "contrast" is "contra" which means "against" or "opposite."
To assert the contrary of; to oppose in words; to take issue with; to gainsay; to deny the truth of, as of a statement or a speaker; to impugn., To be contrary to; to oppose; to resist., To oppose in words; to gainsay; to deny, or assert the contrary of, something.
Oppose,of course!!
The root word of "unmeaningful" is "meaning." By adding the prefix "un-" to "meaning," we create the word "unmeaningful," which conveys the opposite of meaningful.