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Metabolic acidosis is a serious condition within the horse, and mercifully not frequently seen. Laminitis is considered by most to be a metabolic disease itself. For example: when a horse begins to starve, his body metaboizes his own fat stores, causing a buildup of lactic acid. Ketones build up in tissues and deplete alkaline stores. This happens as a result of starvation and metabolic disease, and ends in stretching and death of laminae = laminitis.

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