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Warfarin is considered as an anticoagulants acting by effectively blocking the vitamin K cycle, resulting in inability to produce essential blood-clotting factors --- mainly coagulation factors II (prothrombin), VII (proconvertin).

In addition to this specific metabolic disruption, massive toxic doses of anticoagulant rat poisons, such as Warfarin, cause damage to tiny blood vessels (capillaries), increasing their permeability, causing diffuse internal bleedings (haemorrhagias). These effects are gradual, developing over several days, commonly causing moderate to severe pain from bleeding into muscles and joints. In the final phase of the intoxication, the exhausted rodent collapses in hypovolemic circulatory shock or severe anemia and dies calmly.

Again, it must be a toxic dose of an anticoagulant that will take effect after several days- and can be reversed with ingested Vitamin K.

Therapeutic use of Warfarin in humans as an anticoagulant takes a few days before we see its full effect.

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