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The anucleate condition, as seen in red blood cells, significantly impacts their lifespan by limiting their ability to repair damage and reproduce. Without a nucleus, these cells cannot synthesize new proteins or undergo cell division, leading to a finite lifespan of about 120 days. Consequently, they rely on the continuous production of new cells from the bone marrow to maintain adequate levels in circulation. When red blood cells become senescent or damaged, they are removed from circulation by the spleen and liver, ensuring that only healthy cells remain functional.

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1mo ago

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