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Just like any breed or mix of breeds a great dane/mastiff hybrid is worth only what someone is willing to pay for it. Some "purebred" owners and breeders will say they are mutts and worth nothing however they fail to remember all of their high standard show dogs were developed by mixing breeds so essentially papers mean diddly squat on any dog. An F1 hybrid of any animal will probably be healthier and generally more even tempered than their purebred parents however once you start breeding the hybrids to one another you may start seeing problems. An F1 dane /mastiff is generally longer lived than a dane or mastiff and have less hip and skin problems. As to worth I have seen them for free as a mutt all the way to $2000 as the progeny of hog hunting parents. I think the average is around $200 or so.

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