Yuri Gagarin in Vostok 1
The first fare-paying passenger to fly to space according to NASA was Dennis Tito in 2001. He became the first private individual to pay for a trip to the International Space Station aboard a Russian Soyuz spacecraft.
The first fare-paying passenger in space who flew aboard the STS-41D spacecraft on August 30, 1984, was Charles "Charlie" Walker, an American engineer and businessman who conducted experiments in space as a payload specialist.
The term "space probe" is normally limited to unmanned (robotic) spacecraft. So, no, space probes do not have people aboard them.
The first man in space was Yuri Gagarin, a Soviet cosmonaut. He flew into space aboard the Vostok 1 spacecraft on April 12, 1961. Gagarin required extensive training, a specially designed spacecraft, and a powerful rocket to reach space.
The first female in space was Cosmonaut Valentina Tereshkova (Валенти́на Влади́мировна Терешко́ва) - June 16-19th, 1963, aboard the Russian / Soviet Vostok-6 spacecraft.
Yuri Gagarin was the first man in space. He made his historic flight on April 12, 1961 aboard the Vostok 1 spacecraft.
The first American in space was Alan Shepard, who flew aboard the Freedom 7 spacecraft on May 5, 1961.
Alan Shepard was the first American to travel into space on May 5, 1961, aboard the Freedom 7 spacecraft.
The first dog in space was Laika, a Soviet space dog. She was launched into space aboard the spacecraft Sputnik 2 on November 3, 1957.
Sputnik II A+
The first person in space was Yuri Gagarin, a Soviet cosmonaut who orbited the Earth on April 12, 1961 aboard the Vostok 1 spacecraft.
The first Spacelab was carried aboard the Space Shuttle Columbia on STS-9 (Space Transportation System-9) mission in November 1983.