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Moon blindness has been around a long time. In fact it may be one of the earliest veterinary diseases ever documented. In historical accounts of moon blindness, the disease flareups were thought to be tied to phases of the moon. Over the years, this disease has gone by several names, including periodic opthalmia.

The name in vogue right now is equine recurrent uveitis (ERU). ERU is a chronic, painful, eye disease and is the most common cause of blindness in horses. ERU is incurable but early diagnosis and treatment can improve the long term prognosis. Symptoms of ERU vary, but usually inflammation is involved. After the initial occurrence of eye problems, problems recur both eyes repeatedly.

With each occurrence, damage to the eye worsens. The prevalence of ERU is around 8% according to a 1992 article in Veterinary Clinics of North America: Equine Practice; 1992). Appaloosas are more likely than other breeds to develop ERU and 4 times more likely to become blind as a result of the ERU.

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