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For a normal healthy person a 1:2 or 1:1.5 Inspiratory to Expiratory ratio is expected. Person's with obstructive pulmonary disease processes (COPD, active Asthma reaction) may have a prolonged exhalation 1:3, 1:4 etc. Pulmonary Fibrosis (stiff lung) and damage to certain nueral receptors can cause prolonged inspiration. I/E ratios are manipulated with intubated ventilated patients to achieve a variety of outcomes.

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